Christine Altrock :: Projects

  Department: Microbiology, Immunology, and Molecular Genetics
   
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Design By Sequence

     
Title:“Genetic Calligraphy”
Medium and Dimensions: Inkjet Print on paper mounted on poster board
     
 
click above for larger image
   
     
 
     

Summary: This work uses the genetic code to translate a sentence into a DNA sequence and vice versa. The genetic code table was created by randomly placing words from my original sentence into the boxes. My original sentence was a metaphor for DNA, comparing it to calligraphy. Then like reading a grid (using the far left column for the first base, the top column for the second base, and the far right column for the third base) I translated the sentence into a DNA sequence.I then mutated the original sentence by deleting and substituting words to completely change the meaning of the original sentence. This new sentence was then translated into its own DNA sequence.

For both these sequences I used the complimentary pair (A bonds to U and C to G) to find the complimentary sequences. Then I reverse-translated it to determine the sentence it coded for. I was very surprised that the phrases in the mutated complimentary pair sentence had a very similar meaning to the original sentence and not its complimentary pair sentence (the mutated sentence). It truly related calligraphy to DNA. It was as if the table or the sequences could have some type of self-correcting mechanism built in. How else could one explain the correlation? It seems to be too perfect to be purely coincidental.

 

Original Sentence: Calligraphy is a form that unfolds in time by a dynamic sequence of movements. Each character of the script is made with a precise number of strokes which must be traced to an invariable predetermined sequence. This is a medium that tolerates no error, no correction, no hesitation. ~Simon Leys, One More Art, New York Review, 18 April 1996

Original Sequence: CAA GAU ACA GGU CUA AUA UGC UAC UAA GUU GUA GCC GGC ACG GAA ACC CUU UAG CAC GUC GUG AAU GAC GGA GCG GAG AGU AGA CCA CAU CGU UUA AUU UCG AGC GGG UCU UGG AAC UGA AGG UUC UUU AAA UCA CCG CCU UGU ACU CUC CGA GCA AUG

 

Complimentary Pair Mutated Sequence: GUU CUA UGU CCA GAU UAU ACG AUG AUU CAA CAU CGG CCG CGA CUU UGG GAA AUC GUG CAG CAC UUA CUG CCU GCG CUC UCA UCU GGU GUA GCC GCA AAU UAA AGC UCG CCC AGA ACC UUG ACU UCC AAG AAA UUU GGC GGA UGA GAG CGU UAC

Complimentary Pair Mutated Sentence: A that no which is, movements. To calligraphy must not error no character … is important the traced sequence, precise, no sequence form dynamic sequence hesitation made by invariable an perfect strokes each without correction, it tolerates that of a is number be time

 
     
     
     

Genetic Art Proposal

 

   
Title: "Designer Babies: Reality or Myth?"
   
     
Summary: Imagine your perfect child for a moment. Would it be a he or a she? Would it have blonde, brown, or red hair? How about blue, brown or hazel eyes? Would it be tall, short or average height? What if you could actually determine all these characteristics for your own baby? This used to be just a crazy thought that would never be realistic, right? However, with today‚s technology and sophisticated research this may be closer to reality than previously thought. The consideration of these „designer babies‰ has become more feasible due to great discoveries from the human genome project, cloning and modern molecular biology. Surprisingly, the primary steps of designing your own baby have already taken place, and in some cases have been successful! Is this idea one that we could actually see come true in the near future, or is it just another flashy headline? Could designer babies become a form of art?