Kirsten Knipprath :: Projects

   
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Design By Sequence

Title: Caste In DNA
Medium and Dimensions: green, silver, light blue and dark blue seed beads, gold wire, 5 plastic tubes, needlenose pliers, water, red water color paint, 36” x 1” piece of wood, 18 KT gold spray, drill, super glue, fake flowers, 36” x 2” x 19”

Legend:

Adenine (A) = green seed beads Thymine (T) = silver seed beads
Guanine (G) = light blue seed beads Cytosine (C) = dark blue seed beads

     
 
     
     
 
     

Statement:

My idea incorporates Indian culture and various aspects of its history to represent current studies in science. I was intrigued with the prospect of combining history, ancient culture and DNA with genomic art. I want to represent people’s DNA as viewed through the confines of a specific culture; as viewed from within that culture. India is structured with different castes: Brahmin, Kshatriya, Vaisha, Shudra, and Harijan, in descending order. One’s position in the caste system determines how well one is respected and regarded. Stretching this concept to biology and DNA, it follows that one’s DNA is more “pure” the higher up one is on the caste ladder. Thus at the bottom of the hierarchy, the Harijan, also known as the “untouchables”, would have highly mutated and inferior DNA. I want to represent each of these DNA structures as people from that culture might view it from the older culture, when the caste system was more severe. I hoped to convey that even though their DNA was viewed as inferior, it is still just as beautiful.

Using green seed beads to represent Adenine, silver as Thymine, light blue as Guanine, and dark blue as Cytosine, I strung them accordingly on flexible gold wire. I used 200 bases from the genomic sequence of Ammonifex degensii for each caste’s DNA helix. For the Brahmin caste, I left the DNA sequence unmutated, but for the Kshatriya caste, I mutated about 25% of the sequence. I increased the number of mutations with each succeeding caste (50% for Vaisha, 75% for Shudra, and nearly 100% for Harijan). The water and red paint denotes the bloodshed and ostracism that resulted from these people being deemed as inferior and unclean. The Harijans, the “untouchables”, are therefore shown as having the most impure DNA, and having the most “bloodshed” as a result of this. The richly colored flowers across the top of the board symbolize the puja, or worship, performed to the Hindu gods. All the castes perform puja, and they are all united under their deities.

Upon casual inspection, the mutated DNA appear the same as the ‘perfect’ DNA helix. However, the differing amounts of ‘blood’ in each tube catch the viewer’s eye. The DNA inside the tubes is similar, as is the DNA within humans. The noticeable difference is the ‘blood’, which strives to convey what the mutated DNA alone cannot accomplish.

 

Original Sequence:

Brahmin
GTATACCTTCGGTAGTCTACGGCTACATAGGCTTGAGT
GTGCTCGTTCCCTTCATCCGCAACCACCTGGGGGGCAC
CGGTTTCAGCCTGCTGGCCGGCGTGCTGGTTCTCTCAGT
AATGATCCTGCCTACCATAGCCAGTGTGGCCACTGACTC
CCTGCGCTCCCTTTCTCACATCCTGCGGGAGACGGCCTA
CGCCCTA

 

Mutated Sequence:

Kshatriya
GATACAGTATACCTTCGGTAGTCTACGGCTACATAGGCTTG
AGTGTGCCCTCGTTCTTCATCCGCAACCACCTGGGGGGGAT
ACACACCGGTGCTGGCCGGCTTTCAGCCGTGCTGGTTCTCTC
AGTAATGATCCTGCCTACCATAGCCAGTGTGGCCACTGACTC
CCTGCGCTCCCTTTCTCACATCCTGCGGGACCGGCAGTACGCCCTA

Vaisha
CATATAGCTTCGGTAGGAGTGTTCTACGGCATCTACATAGGCTT
GCTCGCCTTTTCCATCCGCAAGATACACCACCTGGGGGGCACC
GGTTTAAACAGCCTGCCCCCTGGCCGGCGTGCTTTGGCTCTCAG
TAATGTAATGATCCTGCCTACCATAGCCAGTGTGGCCACCCTCA
GTCTGCGCTTTTCCCCTCACATCCTGCGGGAGACGGCCTAGATAC
ACGCCCTA

Shudra
GTATAGTATCCTTCGGCGGTAGTTAGTCTACATCGGCATCATAGT
GTGAGTTCGGCTCGTTCCCCCCTTCATCCGCAACCACCACCTGGG
GGGGGGGGGCACCGGTTTTTTCAGCCTGCCCCTGGCGCGGCCCGT
GCTGGTTCTCTCAGTAATTAATGATGATGATCCTGCCTACCATAGC
CAGGGCTGTCACCTCAGTCCTGCGCTCCCTTTCTCACGCCCATCC
CCCGTGGGAGACGGCCTACTA

Harijan
TACGCCCTACGGTAGTCTACGGCTCCCACATAGGCTCCCTGAGTG
CCCTGCTCCCCGTTCCCCCCTTCACGCCTAATCCACCTGGGAAAG
GGCACCGGTTTCAGCCTGCTCCCGGCCCGGCGCTGCTCCCGGTTCT
CTCAGTAATTCCTAGGCCTACCATTACCATAGCCAGTGTGGCCACT
GACTACTCCCTGCGCTCCCCCCCTCTTTACATCCTGCGGGAGACCC
GGCCCGTATACCTTTTTTTTTTTTTT

 
     
     
     

Genetic Art Proposal

 

   
Title:     
     
Summary: